Myxoid liposarcoma with unusual clinical presentation: imaging diagnosis and histopathologic correlation. A case report

Authors

DOI:

https://doi.org/10.53903/01212095.268

Keywords:

Liposarcoma, Liposarcoma, myxoid, Magnetic resonance imaging

Abstract

Myxoid liposarcoma is the second most frequent malignant neoplasm of all types of liposarcoma, usually located in the lower limbs and retroperitoneum. It is characterized as a slow-growing, painless soft tissue mass that develops especially in the intermuscular and rarely intramuscular compartments and, depending on its cellularity, can become highly metastatic. Imaging diagnosis and its histopathological correlation is essential to provide timely treatment; however, this can become a great challenge due to the lack of specificity of its findings in first line imaging studies that are generally available in hospitals up to second level. This makes the need for more advanced studies essential, such as magnetic resonance imaging (MRI), where the role of the radiologist is
essential for the detection of subtle but pathognomonic findings of this pathology. We present the case of a young adult patient with an unusual presentation of a myxoid liposarcoma who presents with pain and mass at the level of the right buttock; her imaging studies are performed
and analyzed and correlated with histopathological findings.

Downloads

Download data is not yet available.

References

Dei Tos AP. Liposarcomas: diagnostic pitfalls and new insights. Histopathology. 2014;64(1):38-52. http://dx.doi.org/10.1111/his.12311

Sbaraglia M, Bellan E, Dei Tos AP. The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives. Pathologica. 2020;113(2):70-84. http://dx.doi.org/10.32074/1591-951x-213

Loubignac F, Bourtoul C, Chapel F. Myxoid liposarcoma: a rare soft-tissue tumor with a misleading benign appearance. World J Surg Oncol. 2009;7(1). http://dx.doi.org/10.1186/1477-7819-7-42

Petscavage-Thomas JM, Walker EA, Logie CI, Clarke LE, Duryea DM, Murphey MD. Soft-tissue myxomatous lesions: Review of salient imaging features with pathologic comparison. Radiographics. 2014;34(4):964-80. http://dx.doi.org/10.1148/rg.344130110

Benjaminov O, Gutman H, Nyabanda R, Keinan R, Sabach G, Levavi H. Myxoid liposarcoma: An unusual presentation. AJR Am J Roentgenol. 2007;188(3):817-21. http://dx.doi.org/10.2214/ajr.05.0246

Benjaminov O, Gutman H, Nyabanda R, Keinan R, Sabach G, Levavi H. Myxoid liposarcoma: An unusual presentation. Am J Roentgenol. 2007;188(3):817-21. https://doi.org/10.2214/AJR.05.0246

Morán LM, Vega J, Gómez-León N, Royuela A. Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance. Acta Radiol Open. 2022;11(10):20584601221131481. https://doi.org/10.1177/20584601221131481

Chung WJ, Chung HW, Shin MJ, Lee SH, Lee MH, Lee JS, et al. MRI to differentiate benign from malignant soft-tissue tumours of the extremities: a simplified systematic imaging approach using depth, size and heterogeneity of signal intensity. Br J Radiol. 2012;85(1018):e831-6. http://dx.doi.org/10.1259/bjr/27487871

Baheti AD, Tirumani SH, Rosenthal MH, Howard SA, Shinagare AB, Ramaiya NH, et al. Myxoid soft-tissue neoplasms: Comprehensive update of the taxonomy and MRI features. AJR Am J Roentgenol. 2015;204(2):374-85. http://dx.doi.org/10.2214/ajr.14.12888

Tfayli Y, Baydoun A, Naja A, Saghieh S. Management of myxoid liposarcoma of the extremity (Review). Oncol Lett. 2021;22(2). http://dx.doi.org/10.3892/ol.2021.12857

Tuzzato G, Laranga R, Ostetto F, Bubbico E, Vara G, Bianchi G. Primary high-grade myxoid liposarcoma of the extremities: Prognostic factors and metastatic pattern. Cancers. 2022;14(11):2657. https://doi.org/10.3390/cancers14112657

Published

2023-12-30

How to Cite

(1)
Tufiño Sánchez, P. C.; Coronel Brassea , K.; Baquero Jaramillo, M. J.; Revelo Moreira, V. Myxoid Liposarcoma With Unusual Clinical Presentation: Imaging Diagnosis and Histopathologic Correlation. A Case Report. Rev. colomb. radiol. 2023, 34, 6056-6059.